Semaglutide is a medication used to treat type 2 diabetes and, more recently, for weight management. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. These medications work by mimicking the action of a natural hormone called GLP-1, which helps regulate blood sugar levels and appetite.
Semaglutide can be administered via injections, and there are a few different formulations available:
- Ozempic (Semaglutide Subcutaneous Injection): This is a once-weekly injection used to treat type 2 diabetes. It helps control blood sugar levels by increasing insulin secretion, reducing glucagon secretion, and slowing down the emptying of the stomach. By doing so, it can help lower blood sugar levels and promote weight loss.
- Rybelsus (Oral Semaglutide): Rybelsus is a tablet form of semaglutide that can be taken orally. It is used for the treatment of type 2 diabetes. Unlike other GLP-1 agonists, which are administered via injection, Rybelsus can be taken by mouth. However, it should be taken on an empty stomach with a sip of water, and patients are advised not to chew or crush the tablet.
- Wegoby (Semaglutide Subcutaneous Injection): Wegovy is a higher-dose version of semaglutide that was approved by the U.S. Food and Drug Administration (FDA) for chronic weight management in adults with obesity or who are overweight with at least one weight-related comorbidity. It is also administered as a once-weekly injection.
Semaglutide injections can be effective in controlling blood sugar levels in people with type 2 diabetes and can also help with weight loss when used for that purpose. However, like all medications, they may have side effects, and their use should be discussed with a healthcare provider who can determine the appropriate treatment plan based on an individual’s specific medical needs and history.